Oral Azithromycin Versus Doxycycline in Posterior Blepharitis The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Blepharitis , MGD, doxycycline, meibomian gland diesease. Blepharitis (pronounced BLEF-r-EYE-tis) is an ocular condition characterized by chronic inflammation of the eyelid, the severity and time course of which can vary. Doxycycline Use in Cornea and External Disease. Ayad A. Farjo, MD. Common uses for Doxycycline (or Tetracycline or Minocycline) include the following eye diseases I have used doxycycline before but i cant finish the treatment because of gastric side effects and eyelid irritation. Read More 44PM I posted a while back with deep eye pain and diagnosis of Blepharitis. For posterior blepharitis, long-term oral tetracycline, minocycline, or doxycycline is more effective than topical antibiotics, said Dr. Perry, especially for patients with rosacea. “As little as one pill twice a week can maintain a relatively good therapeutic dose in these patients for long periods.” Warm compresses, lid scrubs, and other agents (including doxycycline, cyclosporine emulsion, and artificial tears) may provide added treatment benefit, depending on the type of blepharitis and the presence or absence of concurrent dry eye disease. The only thing that makes sense to me is that blepharitis chart that someone gave a link to a few weeks ago. One of the types of blepharitis was Staphylococcal if I am remembering correctly and the treatment was erythromycin ointment. Doxycycline is a tetracycline antibiotic that fights bacteria in the body. Doxycycline is used to treat many different bacterial infections, such as acne, urinary tract infections, intestinal infections, respiratory infections, eye infections, gonorrhea, chlamydia, syphilis, periodontitis (gum disease), and others. Blepharitis is the medical term for inflamed eyelids. The inflammation is like eczema of the skin, with red, scaly eyelids. You may notice tired, or gritty eyes, which may be uncomfortable in sunlight or a smoky atmosphere. It is used in the management of a variety of conditions, including blepharitis, MGD and RCE. Because doxycycline has a number of applications, it is crucial that clinicians understand both the uses and associated risks of this versatile antibiotic.